Place your order
Fill in the order form and provide all details of your assignment.
Proceed with the payment
Receive the final file
Our discussion, this week, will focus on the thyroid. Respond to the following s
Place your order now for a similar assignment and have exceptional work written by our team of experts, At affordable rates
Our discussion, this week, will focus on the thyroid.
Respond to the following statements and questions, using the included case study, in your discussion submission.
Thyroid hormones exert their effects on cells in a manner similar to steroid hormones; describe the mechanism of action of thyroid hormones.
Why would an imbalance in thyroid hormones have such widespread effects on the body?
Why was goiter observed in George’s case?
Why would calcium homeostasis be impaired in response to removal of the thyroid gland?
What could be used to specifically destroy the thyroid gland and have minimal effects on other cells and tissues in the body?
George is a thirty five year old hardware clerk. During his routine physical he casually mentions to his physician that he seems to be sweating more profusely than normal and most rooms that once were comfortable are now too “hot”. At home a room that his wife and children find to be comfortable causes him to sweat profusely. George also reports that he seems to be losing weight even though his appetite has increased. He also complains that he has a shortened attention span and that he always wants to be moving around. Despite the fact that he feels fatigued, George claims to have difficulty sleeping and seems to have more frequent bowel movements, occasionally accompanied by diarrhea. The physician discovers George has lost 15 pounds since his last physical. In checking his chart, the physician finds that George has a negative history for chronic illnesses, does not smoke, and has a low risk for cardiovascular disease. He does however have a positive family history for autoimmune diseases. His father suffers from idiopathic thrombocytopenia, his mother has been diagnosed with rheumatoid arthritis and his oldest sister was recently diagnosed with systemic lupus erythematosus.
Results of George’s physical examination were within normal ranges with the exception of the following: he demonstrated tachycardia, loud heart sounds, and apparent cardiac arrhythmias accompanied by slight hypertension. These arrhythmias were confirmed by electrocardiogram to be supraventricular in origin. George’s eyeballs appeared large and protruding and his hair was fine and soft. He was also beginning to demonstrate some degree of alopecia. George was also observed to have palmar erythema. palpation of the neck revealed the presence of goiter. Results of blood tests indicated elevated concentrations of thyroid hormones (thyroxin and triiodothyronine), hypercalcemia, and decreased circulating concentrations of lipids. Based on the physical characteristics and the results of the blood tests, George’s physician suspected that George was suffering from some form of hyperthyroidism and sent him to an endocrinologist to confirm the initial diagnosis.
Following the initial consultation and examination, the endocrinologist ordered tests to determine whether George was indeed hyperthyroid. The test results indicated an elevation in the concentration of thyroid hormones in the blood and the presence of thyroid-stimulating antibodies. These antibodies specifically stimulate the thyroid gland by binding with the thyroid stimulating hormone receptor located on the plasma membrane of the follicular cells of the thyroid gland. Based on these results, the endocrinologist concluded that George had Grave’s disease, a form of hyperthyroidism believed to be autoimmune in nature. George was presented with a number of possible treatment options. These included treatment with chemicals (propylthiouracil and methimazole) that decrease the production of thyroid hormones by the thyroid gland, radioisotopic destruction of the thyroid gland by the use of 131I, and surgical removal of the thyroid gland. After considering all the options, especially the possible effects of radiation on gamete development, George chose surgery. Following successful surgery, George was prescribed synthetic thyroid hormone to ensure that his body was receiving adequate thyroid hormone and told to return within 2 months for a follow-up evaluation of circulating thyroid hormone concentrations. He was also cautioned to carefully monitor his calcium intake.
What Will You Get?
Get result-oriented writing and never worry about grades anymore. We follow the highest quality standards to make sure that you get perfect assignments.
Our writers have experience in dealing with papers of every educational level. You can surely rely on the expertise of our qualified professionals.
Your deadline is our threshold for success and we take it very seriously. We make sure you receive your papers before your predefined time.
24/7 Customer Support
Someone from our customer support team is always here to respond to your questions. So, hit us up if you have got any ambiguity or concern.
Sit back and relax while we help you out with writing your papers. We have an ultimate policy for keeping your personal and order-related details a secret.
Still reluctant about placing an order? Our 100% Moneyback Guarantee backs you up on rare occasions where you aren’t satisfied with the writing.
Expository essay of mine is well combined with the pre-made book review. Many thanks for your fast support and quick assistance with the writing.
I needed a research summary to be rewritten according to the stylistic rules used in this college. Everything was done as I asked, I enjoyed the discount and will order again. Didn’t communicate with the writer.
Thanks Elite Academic Essays for helping me sell myself in the best possible way! You’ve done a magnificent job of tying all the pieces of my school application together and creating a holistic image of who I am and what I’ve done in a very bold and captivating manner. Marvelous!